Electrophoresis of the Complement-fixing Antigen of Human Influenza Virus

pH Resistance of Foot-and-Mouth Disease Virus and its Complement-Fixing Antigen

Disruption of Influenza Virus Properties of Degradation Products of the Virus Particle

Two different precipitating antigens have been extracted from vaccinia virus. One, designated the LS antigen (1), is a protein with two antigenically active groups (2, 3); the other, termed the NP antigen, is a nudeoprotein (4). These two antigens apparently comprise a large proportion of the mass of the virus particle. The soluble complement-fixing antigen of influenza virus is usually extract...

Studies on Influenza Virus

Influenza complement fixation tests designed for use with ferret serum are described. Complement-fixing antigens derived from influenza ferret lungs were unsatisfactory due to their low content of soluble antigen; those prepared from mouse lungs or developing chick embryo membranes proved to be better antigenically and were reliable when the various reagents in the test were properly adjusted t...

Evaluating the Immunogenicity of Avian Influenza Virus Nucleoprotein

  Background:  Influenza viruses cause Avian Influenza (AI) is a serious infectious disease belonging to type A Orthomyxovirus. A viral RNA synthesis is due to an interaction of the nucleoprotein (NP) with the viral polymerase. In the present study, we have evaluated the immunogenicity of avian influenza virus nucleoprotein.  Materials & Methods:   An Influenza Virus N9H2 subtype A/Chicken I...

The Immunological Response to Influenza Virus Infection as Measured by the Complement Fixation Test

A quantitative complement fixation test with influenza immune sera and virus antigens obtained from allantoic fluid is described. The method utilizes a photoelectric densitometer which provides a simple, objective, and accurate determination of the hemolytic reaction. The enhancement of the hemolytic activity of complement in the presence of serum or allantoic fluid necessitates a preliminary t...